PSA 10 to 20 ng/ml. This means your cancer is likely to grow slowly and unlikely to spread. Your treatment options may include active surveillance, surgery or radiotherapy with hormone therapy. CPG 3. Gleason score 3 + 4 = 7 (grade group 2), and; PSA 10 to 20 ng/ml, and; T stage of 1 or 2. You will also be in this group if you have: During a PSA test, a small amount of blood is drawn from the arm, and the level of PSA, a protein produced by the prostate, is measured. A higher PSA means that there is a greater chance that you have prostate cancer. Historically, a PSA of 3 or 4 was considered as the threshold of "normal" vs "abnormal.". However, we now know that it The results of the prostate-specific antigen test are reported as nanograms of prostate specific antigens per millimeter of blood. Earlier, 4.0 ng/ml or below was considered the PSA test normal range. However, studies show you can have prostate cancer with prostate-specific antigen levels below 4.0 ng/ml. Test name: PSA a.k.a. Prostate Specific Antigen Condition / Indication: Prostate Cancer Special precautions & notes: PSA should only be sent on serum samples (gold top tubes). EDTA (purple top) or lithium-heparin (green top) tubes are not accepted. Reference range: PSA cut-off values (Local referral guidelines, NICE NG12). Age below 40: use Prostate specific antigen (PSA) This colour chart has been devised to assist with explaining results to patients. Age-related PSA reference intervals are shown in dark green and lime, separated by the age-related median PSA range. J Urol. 2011; 185(5):1650-1655 A PSA level that stays elevated suggests something is going on in the prostate and further tests are required to determine if it is cancer or something else. If your PSA level is over 3.0 ng/ml, your PSA test should be repeated within 1 to 3 months. This is because the PSA sometimes returns to normal levels. What is considered a normal PSA level varies by age group. For example, for men in their 40s, a PSA level of 0 to 2.5 would be considered in the normal range. For men in their 50s, the normal PSA reference ranges As of 22nd February we have changed the PSA thresholds to align with NICE NG 12 suspected cancer: recognition and referral guideline which was updated in December 2021. PSA results: Normal levels usually range from 0 to 4 μg/L, although age-specific values (upper limit of normal) are frequently reported as follows: 40 - 49 years 2.5 μg/L 50 - 59 years 3.5 μg/L 60 - 69 years 4.5 μg/L 70 - 79 years 6.5 μg/L PSA results between 4 and 10 μg/L are considered mildly Biological reference range or cut off: 50‐69 yrs <3.0 ng/mL. A normal prostate‐specific antigen (PSA) level ranges from 0-4 ng/mL. However, the upper level of normal may vary according to age and race, and the PSA test is not diagnostic for prostate cancer. Turnaround time: Same day. mIdZc.